Philosopher Patricia Churchland (BSP 55)

bsp-300-hi Episode 55 of the Brain Science Podcast is an interview with highly respected philosopher Patricia Churchland. Churchland is the author of Neurophilosophy and Brain. She is currently on the faculty of the University of California at San Diego and she was a featured speaker at the annual meeting of the Society for Neuroscience in 2008. In this interview we talked about neurophilosophy, which is an approach to philosophy of mind that gives high priority to incorporating the empiric findings of neuroscience. We also talk about the evolving relationship between philosophy and neuroscience. Churchland shares her enthusiasm for how the discoveries of neuroscience are changing the way we see ourselves as human beings. We also talked a little about the issues of reductionism that I first brought up in Episode 53.

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Dr. Michael Merzenich on Brain Plasiticity (BSP 54)

bsp-300-hi Brain Science Podcast #54 is an interview with Dr. Michael Merzenich, one of the pioneers of neuroplasticity. We talk about how the success of the cochlear implant revealed unexpected plasticity in adult brains and about how brain plasticity can be tapped to improve a wide variety of problems including dyslexia, autism, damage from disease and injury. Healthy people of all ages can also tap the resource of brain plasticity to help maintain and improve their mental functions.

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Vaccines DO NOT cause Autism (B&I 25)

offit-1 Paul Offit, MD Episode 25 of Books and Ideas is an interview with Dr. Paul Offit, author of Autism's False Prophets: Bad Science, Risky Medicine, and the Search for a Cure. I consider this the most important episode that I have ever released because despite overwhelming scientific evidence that shows NO connection between vaccines and autism, vaccine opponents continue to discourage parents from having their children vaccinated against preventable and potentially fatal childhood diseases. Epidemics of measles and hemophilis influenza type B meningitis are beginning to emerge among unvaccinated children. In this interview we talk about the scientific evidence that vaccines DO NOT cause autism, but we also examine why the controversy continues despite the evidence. Most importantly we examine the growing threat posed by the increasing number of unvaccinated children in the US. As Dr. Offit observes "The threat is not theoretical anymore." It is very real.

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ADDITIONAL SHOW NOTES

I recommend Dr. Offit's book Autism's False Prophets to everyone because of its thorough examination of the vaccine-autism controversy. He examines the evidence from both sides, while showing compassion for why parents are easily confused and frightened by claims that physicians and scientists have dismissed. The book is unlikely to dissuade those who are convinced by the tactics of vaccine opponents, but it will be a valuable resource to parents who want a clear explanation that includes a sober account of the risks of not vaccinating their children. Physicians and scientists will also benefit from reading this book because it provides an important case study in how lack of scientific literacy can threaten public health.

Links:

References:

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Follow-up interview with Frank Wilczek (B&I 24)

wilczek Episode 24 of Books and Ideas is a follow-up interview with Nobel Prize winning physicist. Dr. Frank Wilczek. We discuss the questions that we didn't get around to in Episode 23, including the 2008 Nobel Prize in Physics, String Theory, and dark matter and dark energy. Dr. Wilczek also answers some questions from listeners and tells us a little about his current work.

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Main Topics from this Episode:

  • 2008 Nobel Prize in Physics
  • String Theory: a look at how it differs from the standard model and the question of whether it can be tested
  • Dark Matter and Dark Energy: 95% of the matter in the universe remains unexplained!
  • Anti-matter: where science meets science fiction
  • Dr. Wilczek's research: Could axions be dark matter? Using quantum mechanics to create new electronics.
  • Questions from listeners
Announcements: Episodes 23 and 24 are based on Dr. Wilczek's excellent book:

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Synapse Evolution with Dr. Seth Grant (BSP 51)

Episode 51 of the Brain Science Podcast is an interview with Dr. Seth Grant from Cambridge University, UK.  Dr. Grant's work focuses on the proteins that make up the receptors within synapses. (Synapses are the key structures by which neurons send and receive signals.) By comparing the proteins that are present in the synapses in different species Dr. Grant has come to some surprising conclusions about the evolution of the synapse and the evolution of the brain. (Read more...)

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Dr. Brenda Milner: Pioneer of Memory Research (BSP 49)

Brain Science Podcast #49 is an interview with pioneering neuroscientist, Brenda Milner, PhD. Dr. Milner is known for her contributions to understanding memory and her work with split-brain patients. Her work as an experimental psychologist has been fundamental to the emergence of the field of cognitive neuroscience. This interview is a follow-up of Dr. Milner's recent interview with Dr. Marc Pelletier on Futures in Biotech. I highly recommend listening to both interviews.

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Interview with Nobel Physicist Frank Wilczek (B&I 23)

Episode 23 of Books and Ideas is an interview with Frank Wilczek, PhD from MIT. Dr. Wilczek won the Nobel Prize for Physics in 2004 and recently published an excellent book aimed at general readers: Lightness of Being: Mass, Ether, and the Unification of Forces. This book provides an excellent review of current ideas about the meaning of both matter and space. In his interview Dr. Wilczek helps us understand the current evidence that matter is actually made of particles that are massless. He says "I jokingly say that the more important law is Einstein's Second Law m=E/c² (which is of course just a rearrangement of E=mc²) but this suggests that what we really should be doing is not explaining energy in terms of mass, but explaining mass in terms of energy." The second surprisingly concept that Dr. Wilczek helps us tackle in this interview is the idea that space is not empty. "Space is a medium with a variety of properties that make it, not only an important component of reality, but really the primary component of reality." These ideas are supported by experimental evidence, but the Large Hadron Collider (LHC) near Geneva, Switzerland is expected to expand knowledge even further. The purpose of the LHC is a main focus of this interview. Dr. Wilczek has agreed to come back on Books and Ideas to answer questions about dark matter and string theory.

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Additional Show Notes and Links: Frank Wilczek, PhD Other podcasts mentioned in this episode Recommended Reading: Announcements:

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Our "Big Brain" with Dr. Gary Lynch (BSP 48)

Episode 48 of the Brain Science Podcast is an interview with Gary Lynch, PhD, co-author of Big Brain: The Origins and Future of Human Intelligence. While it is generally agreed that one of the most striking features of the human brain is its large size, not everyone agrees about how and why our brains came to be so large. In this interview Dr. Lynch presents some rather radical theories about how the human brain evolved. We discuss the pros and cons of his theories as well as the challenges faced by researchers trying to work in this field.

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The next episode of the Brain Science Podcast will be an interview with Dr. Brenda Milner. This interview will is a follow-up to Marc Pelletier's excellent interview of Dr. Milner on Futures in Biotech: http://www.twit.tv/fib33.

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Dr. Pamela Gay talks about the Milky Way on Brains Matter

Dr. Pamela Gay, host of the popular Astronomy Cast was interviewed for the latest episode of Brains Matter. In this interview Dr. Gay discusses the recent discovery that our Milky Way has only two arms instead of four. I recommend this episode to everyone who enjoyed Pam's interview in Episode 14 of Books and Ideas and to all the fans of the Astronomy Cast.

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Brains Matter is part of SCIENCEPODCASTERS.ORG. We recently moved our website, so be sure to update your book marks.

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Dr. Eugenie Scott on Teaching Evolution (B&I 21)

Eugenie Scott, the Executive Director of the National Center for Science Education, was interviewed in Episode 21 of Books and Ideas. The focus of our conversation was the importance of teaching evolution in the public schools. Dr. Scott and the NCSE have worked for over 20 years to promote the teaching of evolution because it is an essential component of a modern education in the life sciences. Unfortunately, nearly 150 years after Darwin's On the Origin of Species (1859) many Americans still reject this fundamental idea and much of Scott's work is focused on trying to keep creationism and so-called Intelligent Design out of school curriculum. Recently the NCSE launched a very valuable site called Expelled Exposed, which focuses on exposing the many inaccuracies presented in Ben Stein's recent pro-intelligent design "documentary" Expelled. One of the things that has come out in numerous interviews is that the producers of the film mislead all the pro-evolution guests that appear in the film. We discuss this briefly near the end of the interview, but it was not the focus of our discussion. (see below for more links regarding Expelled) Since Dr. Scott has been interviewed about Expelled and Expelled Exposed on several other podcasts, I wanted to focus our interview more on the importance of accurate science education. Also, we discussed the fact that despite the claims of right-wing fundamentalists there are many Christians and people of other faiths who accept the theory of evolution as scientifically valid. Accepting evolution does not mean one is choosing atheism. I think this is a very important distinction because while atheists are outspoken in their support of evolution they represent a small minority. I was encouraged to learn from Dr. Scott that the NCSE is working closely with religious leaders and scientists of faith to try to educate their members. Since Books and Ideas reaches an international audience I thought that it was important that we discuss the origins of the evolution versus creationism controversy, which is unique to the United States. Scott does an excellent job of explaining how our unique religious heritage along with our locally controlled school systems combine to create a situation that most of the world find's rather mystifying. Her book Evolution vs. Creationism: An Introduction also provides an excellent overview of the subject from both an historical and scientific prospective. Finally, we talk about the importance of evolution as a basic idea in modern biology. While we didn't dwell on this, I think we are both concerned about the implications for the future if a majority of young Americans are reaching college without a solid foundation in the principles of evolution. We also talked about why intelligent design fails to meet the basic definition of a scientific theory since it provides no testable hypotheses. Dr. Scott also provides a excellent review of the basic writings for those who want to learn more.

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Links and References: Other Books mentioned by Dr. Scott:
  • Of Pandas and People: The Central Question of Biological Origins by Percival Davis and Dean H. Kenyon : the 1989 textbook that introduced the term “intelligent design”
  • Darwin on Trial by Phillip E. Johnson, 1991.
  • Darwin’s Black Box: The Biochemical Challenge to Evolution by Michael J. Behe
  • The Design Inference: Eliminating Chance through Small Probabilities by William A. Dembski
  • Behe MJ, Snoke DW. 2004. Simulating evolution by gene duplication of protein features that require multiple amino acid residues. Protein Science 10:2651-64.
Responses to Expelled Exposed by Christians

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Mindfulness Meditation with Delany Dean (B&I 20)

Delany DeanEpisode 20 of Books and Ideas is an interview with forensic psychologist Delany Dean, PhD. Dr. Dean began her career as a criminal lawyer but his interest in the mind and the brain lead her to a second career as a clinical psychologist. Besides forensic psyschology she has extensive experience with therapies based on the use of mindfulness meditation. In this interview, Dr. Campbell and Dr. Dean share there personal experiences with meditation, and Dr. Dean explains why she feels mindfulness meditation provides a extremely valuable tool for helping people deal with a wide range of problems, including the stress that we all face from time to time. They also give practical advise for listeners interested in beginning a mindfulness practice.

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Links and References:

Mind Expressions: Delany's Dean's blog Teachers and Scientists mentioned in the interview: Books and Other Resources for Beginners: You can find more references at the Brain Science Podcast Discussion Forum where there is on-going thread devoted to meditation and the Brain. There is also a section for discussing episodes of Books and Ideas.

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Could the eye have evolved? The answer is YES!

I have been meaning to recommend the excellent website Expelled Exposed, which documents all the lies and misleading statements in Ben's Stein's creationist "documentary," Exposed. A central claim is that professors who believe in intelligent design are being persecuted, a claim that is totally unfounded. Expelled Exposed was created by the National Center for Science Education. You can hear an excellent interview with Director Eugenie Scott on the April 9th episode of Science Talk, Scientific American's podcast. One of the claims that is popular with ID proponents is the idea that the eye is too complex to have been the product of evolution. Actually, as was pointed in David Bainbridge's excellent book, Beyond the Zonules of Zinn: A Fantastic Journey Through Your Brain, nothing could be further from the truth, because there is evidence that eyes have actually evolved a surprising number of times. (For more on Bainbridge's book listen to Episode 32 of the Brain Science Podcast.) To learn more about the evidence for the evolution of the eye check out this new video which NCSE has posted on YouTube: http://www.youtube.com/watch?v=fOtP7HEuDYA
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Dan Rather Presents Neuroplasticity

Today HDNet™ is reshowing an episode of Dan Rather Reports called "Mind Science." It is an excellent review of neuroplasticity. It includes interviews with several leading scientists in the field. I especially enjoyed seeing Nobel Laureate Eric Kandel talk about his work with memory. (I talked about Kandel's work on the Brain Science Podcast in Episode 3 and Episode 12.) "Mind Science" also features the Dalai Llama and scientist Richard Davidson talking about the evidence that meditation can change the brain. Rather interviews Sharon Begely about her book Train Your Mind, Change Your Brain: How a New Science Reveals Our Extraordinary Potential to Transform Ourselves (which I discussed in detail in Episode 10 of the Brain Science Podcast). Other scientists featured in the episode include Michael Merzenich on improving brain function as we age and Dr. Edward Taub on his revolutionary approach to stroke rehabilitation. (My show notes for Episode 10 include links for all the scientists interviewed by Rather.) It was particulary gratifying to see Dr. Kandel endorse Ed Taub's Constraint-Induced Movement Therapy. Dr. Taub was interviewed in Episode 28 of the Brain Science Podcast. If you don't get HDNet™ you can watch Dan Rather Reports on-line, via podcast or on Facebook. Summary of relevant episodes of the Brain Science Podcast: itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email

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Exercise and the Brain (BSP 33)

Episode 33 of the Brain Science Podcast is an interview with Harvard physician, Dr. John Ratey about his new book Spark: The Revolutionary New Science of Exercise and the Brain. johnpic_profile.jpgJohn J Ratey, MD We explore the exciting evidence about how exercise helps the brain. It stimulates the release of a number of different neurotransmitters and neuropeptides, but probably more importantly it helps keeps these compounds balanced. We consider why exercise is so important in dealing with stress, in treating a wide range of mental illnesses including depression, anxiety, and attention deficit disorder. There is also evidence that exercise improves our ability to learn and our ability to avoid the loss of mental agility associated with aging. Listen to Episode 33 Now. This episode contains information that everyone can use. I hope you will share it with your friends and family. Links and References: spark-ratey.jpgSpark: The Revolutionary New Science of Exercise and the Brain (2008) by John J. Ratey Dr. Ratey's website: Go here for more interview of Dr. Ratey and also to find links to the latest research about exercise and the brain. Listen to Dr. Ratey's Interview Now. Share your comments on the Discussion Forum Audience Survey itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email

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A Brief Introduction to Brain Anatomy (BSP 32)

zonulesofzinn.jpg Episode 32 of the Brain Science Podcast is a whirlwind (55 minute) tour of brain anatomy. It is based on David Bainbridge's new book: Beyond the Zonules of Zinn: A Fantastic Journey Through Your Brain (2008). Within the next few days I will be expanding the show notes to include key illustrations from the book. I want to thank David for sharing these images and I encourage everyone to read the book. Listen to Episode 32 (Transcript coming soon, see below*) Share your comments on the Discussion Forum Audience Survey itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email

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*As of 12/9/08 this episode has not yet been transcribed. When it is transcribed the show notes on the main Brain Science Podcast will be updated. Please send email to docartemis at gmail.com if you would like to be notified when the transcript is ready (it will be several months).

Note: If you would like to comment on this episode please go the the show notes on the Brain Science Podcast website or to the Discussion Forum at http://brainscienceforum.com.

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Brain Rhythms with György Buzsáki (BSP 31)

rhythmsofthebrain.jpg György Buzsáki, author of Rhythms of the Brain (OUP 2006) is a Professor of Neuroscience at Rutgers University. His book is a comprehensive review of the current state of research in the field of brain oscillations. It includes the role of these oscillations in sleep and memory. In episode 31 of the Brain Science Podcast Dr. Buzáki explains why the rhythms of the brain are important and reflects on why this field has been neglected by some neuroscientists. I think he makes a convincing case for the position that these rhythms are an essential component of brain function. Listen to Dr. György Buzsáki's interview about Brain Rhythms Transcript of Episode 31 SHOW NOTES: Partial List of Scientists Mentioned:
  • Stephen Strogatz: known for his discovery of "small world" architecture
    • His 2003 bestseller Sync: The emerging science of spontaneous order is aimed at a general audience
  • Nancy Kopell: mathematician
    • Buzsaki recommends her review of the analytical approaches to neuronal oscillators: We got Rhythm: Dynamical Systems of the Nervous System. N Am Math Soc 47: 6-16 (2000).
  • Zoltán Néda (Bebes-Bolyai University Romania): the spontaneous synchronization of hand clapping
  • Hermann Haken: German laser physicist who studies bidirectional causation
    • The Science of Structure: Synergetics (1984)
  • John O'Keefe (University College, London): along with Lynn Nadel he discovered how the hippocampus forms a cognitive map of the world
  • David McCormick (Yale University): showed that neurons from the thalamus of a ferret can oscillate spontaneously
    • He has also studied the oscillations of place cells in the hippocampus
  • David Hubel and Thorston Wiesal: along with Vernon Montcastle they pioneered the use of single neuron recordings in the neocortex of casts and monkeys
    • Montcastle, VB (1997) "The Columnar Organization of the Neocortex." Brain 102:01-722.
  • Claude Shannon: founder of Information Theory
  • Jan Born (University of Lübeck, Germany): experiments with how sleep improves both memory and problem solving
Topics and questions:
  • Basics of oscillations and synchrony
  • What functions are accomplished by brain rhythms?
  • The role of hippocampal ripples in memory
  • What happens to our brain rhythms while we sleep
  • The importance of synchrony in saving energy in the brain
This episode will appeal to listeners with a background in math or engineering, but Dr. Buzsáki provides numerous everyday examples that make the material accessible to everyone. Listen to this episode now. Share your comments on the Discussion Forum Audience Survey itunes-chicklet.gif Subscribe via iTunes™ Subscribe in a reader or podcatcher Subscribe to Brain Science Podcast with Dr. Ginger Campbell by Email

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Embracing the Evidence for Evolution is not Always Easy

This week's Science magazine includes a profile of Canadian paleontologist Stephen Godfrey. What makes his story unusual is that he was raised as a fundamentalist Christian to believe in the creationist dogma of a 6,000 year-old earth. The article highlights why it can be very difficult to make such a transition since it also makes one an outsider. Not only may the young person lose their place in their religious community, but they may find find themselves reluctant to share their past with their new scientist colleagues who generally tend to assume that all creationists are intellectually inferior. This article interested me on two levels. For one thing, I think it makes some points that need to be acknowledged if mainstream scientists hope to win over potential young scientists from the admittedly growing influence of the creationists. On a more personal level, it reminded me of my own personal journey when back in my early 20's (in the late 1970's) I left Jehovah's Witnesses largely because I realized that they had totally misrepresented the scientific evidence about evolution. I reached this conclusion after studying the evidence myself. While I felt a sense of intellectual liberation, I also felt the pain of losing my religious community. I think it is important to realize that since humans are social by nature we have to realize that these ties are extremely powerful and can be a formidable obstacle to getting people to examine their beliefs. EVOLUTION: Crossing the Divide by Jennifer Couzin. Science 22 February 2008: Vol. 319. no. 5866, pp. 1034 - 1036
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